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Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy

Myosin 5a is a dual-headed molecular motor that transports cargo along actin filaments. By following the motion of individual heads with interferometric scattering microscopy at nm spatial and ms temporal precision we found that the detached head occupies a loosely fixed position to one side of acti...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Andrecka, Joanna, Ortega Arroyo, Jaime, Takagi, Yasuharu, de Wit, Gabrielle, Fineberg, Adam, MacKinnon, Lachlan, Young, Gavin, Sellers, James R, Kukura, Philipp
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391024/
https://ncbi.nlm.nih.gov/pubmed/25748137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05413
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