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Expansion of B-1a Cells with Germline Heavy Chain Sequence in Lupus Mice
B6.Sle1.Sle2.Sle3 (B6.TC) lupus-prone mice carrying the NZB allele of Cdkn2c, encoding for the cyclin-dependent kinase inhibitor P18(INK4), accumulate B-1a cells due to a higher rate of proliferative self-renewal. However, it is unclear whether this affects primarily early-appearing B-1a cells of fe...
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| Publicat a: | Front Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805591/ https://ncbi.nlm.nih.gov/pubmed/27047495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00108 |
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