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Mitigation of Myocardial Fibrosis by Molecular Cardiac Surgery Mediated Gene Overexpression
OBJECTIVE: Heart failure is accompanied by upregulation of transforming growth factor beta signaling, accumulation of collagen and dysregulation of sarcoplasmic reticulum calcium ATPase cardiac isoform 2a (SERCA2a). We examined the fibrotic response in small and large myocardial infarct and the effe...
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| Publicado en: | J Thorac Cardiovasc Surg |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805528/ https://ncbi.nlm.nih.gov/pubmed/26769537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.11.031 |
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