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Targeting Glycolysis in Leukemia: A novel inhibitor 3-BrOP in combination with Rapamycin
Rapidly proliferating solid tumor cells are often dependent on glycolysis for ATP production even in normoxia (the Warburg effect), however it is not yet clear whether acute leukemias have a similarly increased dependence on aerobic glycolysis. We report that all leukemia subtypes (pre-B ALL, T-ALL...
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| Опубликовано в: : | Leuk Res |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805370/ https://ncbi.nlm.nih.gov/pubmed/21316758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.12.028 |
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