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Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is an aggressive malignant disorder of lymphoid progenitor cells in both children and adults. Although improvements in contemporary therapy and development of new treatment strategies have led to dramatic increases in the cure rate in children with ALL,...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Shi, Pei-Jie, Xu, Lu-Hong, Lin, Kang-Yu, Weng, Wen-jun, Fang, Jian-Pei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757994/
https://ncbi.nlm.nih.gov/pubmed/26892465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0241-x
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