Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is an aggressive malignant disorder of lymphoid progenitor cells in both children and adults. Although improvements in contemporary therapy and development of new treatment strategies have led to dramatic increases in the cure rate in children with ALL,...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Shi, Pei-Jie, Xu, Lu-Hong, Lin, Kang-Yu, Weng, Wen-jun, Fang, Jian-Pei
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757994/
https://ncbi.nlm.nih.gov/pubmed/26892465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0241-x
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