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The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma

Children with high-risk and recurrent neuroblastoma have poor survival rates, and novel therapies are needed. Many cancer cells have been found to preferentially employ the glycolytic pathway for energy generation, even in the presence of oxygen. 3-BrOP is a novel inhibitor of glycolysis, and has de...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Levy, Alejandro G., Zage, Peter E., Akers, Lauren J., Ghisoli, Maurizio L., Chen, Zhao, Fang, Wendy, Kannan, Sankaranarayanan, Graham, Timothy, Zeng, Lizhi, Franklin, Anna R., Huang, Peng, Zweidler-McKay, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831635/
https://ncbi.nlm.nih.gov/pubmed/20890785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9551-y
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