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Targeting Glycolysis in Leukemia: A novel inhibitor 3-BrOP in combination with Rapamycin
Rapidly proliferating solid tumor cells are often dependent on glycolysis for ATP production even in normoxia (the Warburg effect), however it is not yet clear whether acute leukemias have a similarly increased dependence on aerobic glycolysis. We report that all leukemia subtypes (pre-B ALL, T-ALL...
שמור ב:
| הוצא לאור ב: | Leuk Res |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805370/ https://ncbi.nlm.nih.gov/pubmed/21316758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.12.028 |
| תגים: |
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