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A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle

Muscular manifestation of myotonic dystrophy type 1 (DM1), a common inheritable degenerative multisystem disorder, is mainly caused by expression of RNA from a (CTG·CAG)(n)-expanded DM1 locus. Here, we report on comparative profiling of expression of normal and expanded endogenous or transgenic tran...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Gudde, Anke E. E. G., González-Barriga, Anchel, van den Broek, Walther J. A. A., Wieringa, Bé, Wansink, Derick G.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805313/
https://ncbi.nlm.nih.gov/pubmed/26908607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw042
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