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Somatic CTG•CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy
BACKGROUND: Trinucleotide instability is a hallmark of degenerative neurological diseases like Huntington's disease, some forms of spinocerebellar ataxia and myotonic dystrophy type 1 (DM1). To investigate the effect of cell type and cell state on the behavior of the DM1 CTG•CAG repeat, we stud...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1940261/ https://ncbi.nlm.nih.gov/pubmed/17645799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-61 |
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