Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer

The blood brain barrier (BBB) is compromised in brain metastases, allowing for enhanced drug permeation into brain. The extent and heterogeneity of BBB permeability in metastatic lesions is important when considering the administration of chemotherapeutics. Since permeability characteristics have be...

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Bibliographic Details
Published in:Clin Exp Metastasis
Main Authors: Adkins, Chris E., Mohammad, Afroz S., Terrell-Hall, Tori, Dolan, Emma L., Shah, Neal, Sechrest, Emily, Griffith, Jessica, Lockman, Paul R.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804888/
https://ncbi.nlm.nih.gov/pubmed/26944053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-016-9784-z
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