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Enantiospecific Alkynylation of Alkylboronic Esters

Enantioenriched secondary and tertiary alkyl pinacolboronic esters undergo enantiospecific deborylative alkynylation through a Zweifel‐type alkenylation followed by a 1,2‐elimination reaction. The process involves use of α‐lithio vinyl bromide or vinyl carbamate species, for which application to Zwe...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wang, Yahui, Noble, Adam, Myers, Eddie L., Aggarwal, Varinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804747/
https://ncbi.nlm.nih.gov/pubmed/26934427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201600599
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