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The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity

Autoreactive B cells play critical roles in a large diversity of autoimmune diseases, but the molecular pathways controlling these cells remain poorly understood. We performed an in vivo functional screen of a lymphocyte-expressed miRNA library and identified the microRNA miR-148a as a potent regula...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Gonzalez-Martin, Alicia, Adams, Brian D, Lai, Maoyi, Shepherd, Jovan, Salvador-Bernaldez, Maria, Salvador, Jesus M, Lu, Jun, Nemazee, David, Xiao, Changchun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803625/
https://ncbi.nlm.nih.gov/pubmed/26901150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3385
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