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All roads lead to PP2A: Exploiting the therapeutic potential of this phosphatase

Protein phosphatase 2A is a serine/threonine phosphatase involved in the regulation of many cellular processes. A confirmed tumor suppressor protein, PP2A is genetically altered or functionally inactivated in many cancers highlighting a need for its therapeutic reactivation. In this review we will d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:FEBS J
Hauptverfasser: Sangodkar, Jaya, Farrington, Caroline, McClinch, Kimberly, Galsky, Matthew D., Kastrinsky, David B., Narla, Goutham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803620/
https://ncbi.nlm.nih.gov/pubmed/26507691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13573
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