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Targeting PP2A in cancer: Combination therapies
The serine/threonine phosphatase PP2A regulates a vast portion of the phosphoproteome including pathways involved in apoptosis, proliferation and DNA damage response and PP2A inactivation is a vital step in malignant transformation. Many groups have explored the therapeutic venue of combining PP2A r...
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| Veröffentlicht in: | Biochim Biophys Acta Mol Cell Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6436821/ https://ncbi.nlm.nih.gov/pubmed/30401535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2018.08.020 |
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