Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3

AIM: Human periodontitis is associated with overactivation of complement, which is triggered by different mechanisms converging on C3, the central hub of the system. We assessed whether the C3 inhibitor Cp40 inhibits naturally-occurring periodontitis in non-human primates. MATERIALS AND METHODS: Non...

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Detaylı Bibliyografya
Yayımlandı:J Clin Periodontol
Asıl Yazarlar: Maekawa, Tomoki, Briones, Ruel A., Resuello, Ranillo R.G., Tuplano, Joel V., Hajishengallis, Evlambia, Kajikawa, Tetsuhiro, Koutsogiannaki, Sophia, Garcia, Cristina A.G., Ricklin, Daniel, Lambris, John D., Hajishengallis, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803614/
https://ncbi.nlm.nih.gov/pubmed/26728318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpe.12507
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