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HIGH MOBILITY GROUP-BOX 1 (HMGB1) LEVELS ARE INCREASED IN AMNIOTIC FLUID OF WOMEN WITH INTRA-AMNIOTIC INFLAMMATION-DETERMINED PRETERM BIRTH, AND THE SOURCE MAY BE THE DAMAGED FETAL MEMBRANES
BACKGROUND: High Mobility Group Box-1 (HMGB1) is considered a prototype alarmin molecule. Upon its extracellular release, HMGB1 engages pattern recognition receptors and the Receptor for Advanced Glycation End (RAGE) followed by an outpouring of inflammatory cytokines, including interleukin (IL)-6....
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| Pubblicato in: | Cytokine |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803598/ https://ncbi.nlm.nih.gov/pubmed/26954343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2016.02.013 |
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