HIGH MOBILITY GROUP-BOX 1 (HMGB1) LEVELS ARE INCREASED IN AMNIOTIC FLUID OF WOMEN WITH INTRA-AMNIOTIC INFLAMMATION-DETERMINED PRETERM BIRTH, AND THE SOURCE MAY BE THE DAMAGED FETAL MEMBRANES

BACKGROUND: High Mobility Group Box-1 (HMGB1) is considered a prototype alarmin molecule. Upon its extracellular release, HMGB1 engages pattern recognition receptors and the Receptor for Advanced Glycation End (RAGE) followed by an outpouring of inflammatory cytokines, including interleukin (IL)-6....

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Detalhes bibliográficos
Publicado no:Cytokine
Main Authors: Baumbusch, Margaret A., Buhimschi, Catalin S., Oliver, Emily A., Zhao, Guomao, Thung, Stephen, Rood, Kara, Buhimschi, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803598/
https://ncbi.nlm.nih.gov/pubmed/26954343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2016.02.013
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