INTERLEUKIN-6 TRANS-SIGNALING SYSTEM IN INTRA-AMNIOTIC INFLAMMATION, PRETERM BIRTH AND PRETERM PREMATURE RUPTURE OF THE MEMBRANES

Classic IL-6 signaling is conditioned by the transmembrane receptor (IL-6R) and homodimerization of gp130. During trans-signaling, IL-6 binds to soluble IL-6R (sIL-6R) enabling activation of cells expressing solely gp130. Soluble gp130 (sgp130) selectively inhibits IL-6 trans-signaling. To character...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Lee, Sarah Y., Buhimschi, Irina A., Dulay, Antonette T., Ali, Unzila A., Zhao, Guomao, Abdel-Razeq, Sonya S., Bahtiyar, Mert O., Thung, Stephen F., Funai, Edmund F., Buhimschi, Catalin S.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800180/
https://ncbi.nlm.nih.gov/pubmed/21282511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003587
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares