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Control of T cell antigen reactivity via programmed TCR downregulation
The T cell receptor (TCR) is unique in that its affinity for ligand is unknown prior to encounter and can vary by orders of magnitude. How the immune system regulates individual T cells that display highly different reactivity to antigen remains unclear. Here we identified that activated CD4(+) T ce...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803589/ https://ncbi.nlm.nih.gov/pubmed/26901151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3386 |
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