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Optimal design of gene knockout experiments for gene regulatory network inference

Motivation: We addressed the problem of inferring gene regulatory network (GRN) from gene expression data of knockout (KO) experiments. This inference is known to be underdetermined and the GRN is not identifiable from data. Past studies have shown that suboptimal design of experiments (DOE) contrib...

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書誌詳細
出版年:Bioinformatics
主要な著者: Ud-Dean, S. M. Minhaz, Gunawan, Rudiyanto
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803391/
https://ncbi.nlm.nih.gov/pubmed/26568633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv672
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