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Noise Expands the Response Range of the Bacillus subtilis Competence Circuit

Gene regulatory circuits must contend with intrinsic noise that arises due to finite numbers of proteins. While some circuits act to reduce this noise, others appear to exploit it. A striking example is the competence circuit in Bacillus subtilis, which exhibits much larger noise in the duration of...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Mugler, Andrew, Kittisopikul, Mark, Hayden, Luke, Liu, Jintao, Wiggins, Chris H., Süel, Gürol M., Walczak, Aleksandra M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803322/
https://ncbi.nlm.nih.gov/pubmed/27003682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004793
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