Noise Expands the Response Range of the Bacillus subtilis Competence Circuit

Gene regulatory circuits must contend with intrinsic noise that arises due to finite numbers of proteins. While some circuits act to reduce this noise, others appear to exploit it. A striking example is the competence circuit in Bacillus subtilis, which exhibits much larger noise in the duration of...

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Publicat a:PLoS Comput Biol
Autors principals: Mugler, Andrew, Kittisopikul, Mark, Hayden, Luke, Liu, Jintao, Wiggins, Chris H., Süel, Gürol M., Walczak, Aleksandra M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803322/
https://ncbi.nlm.nih.gov/pubmed/27003682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004793
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