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Noise Expands the Response Range of the Bacillus subtilis Competence Circuit

Gene regulatory circuits must contend with intrinsic noise that arises due to finite numbers of proteins. While some circuits act to reduce this noise, others appear to exploit it. A striking example is the competence circuit in Bacillus subtilis, which exhibits much larger noise in the duration of...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Mugler, Andrew, Kittisopikul, Mark, Hayden, Luke, Liu, Jintao, Wiggins, Chris H., Süel, Gürol M., Walczak, Aleksandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803322/
https://ncbi.nlm.nih.gov/pubmed/27003682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004793
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