In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells. This could be due to short half-life of hematopoietic stem cells in culture or...

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Udgivet i:Haematologica
Main Authors: Vanhee, Stijn, De Mulder, Katrien, Van Caeneghem, Yasmine, Verstichel, Greet, Van Roy, Nadine, Menten, Björn, Velghe, Imke, Philippé, Jan, De Bleser, Dominique, Lambrecht, Bart N., Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Vandekerckhove, Bart
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803135/
https://ncbi.nlm.nih.gov/pubmed/25381126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.112144
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