BRCA testing, treatment patterns and survival in platinum-sensitive recurrent ovarian cancer – an observational cohort study

BACKGROUND: Breast cancer associated (BRCA) genes are critical for DNA repair. Mutations in BRCA1 and BRCA2 (BRCAm) result in loss of these repair mechanisms and potential carcinogenesis. Germline BRCAm are common in ovarian carcinomas, particularly in platinum-sensitive disease. The increased preva...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Ovarian Res
मुख्य लेखकों: Unni, Sudhir K., Schauerhamer, Marisa B., Deka, Rishi, Tyczynski, Jerzy E., Fernandes, Ancilla W., Stevens, Vanessa, Brixner, Diana I., Stenehjem, David D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2016
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802840/
https://ncbi.nlm.nih.gov/pubmed/27004793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-016-0227-x
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