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BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence
The BRE gene, alias BRCC45, produces a 44 kDa protein that is normally distributed in both cytoplasm and nucleus. In this study, we used adult fibroblasts isolated from wild-type (WT) and BRE knockout (BRE(−/−)) mice to investigate the functional role of BRE in DNA repair and cellular senescence. We...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4802329/ https://ncbi.nlm.nih.gov/pubmed/27001068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23506 |
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