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DDB2, an Essential Mediator of Premature Senescence

Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and cancer therapy. Here, we reveal a novel function of the nucleotide excision repair protein DDB2 in the accumulation of ROS in a manner that is essential for premature senescence. DDB2-d...

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Bibliografische gegevens
Hoofdauteurs: Roy, Nilotpal, Stoyanova, Tanya, Dominguez-Brauer, Carmen, Park, Hyun Jung, Bagchi, Srilata, Raychaudhuri, Pradip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876515/
https://ncbi.nlm.nih.gov/pubmed/20351176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01480-09
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