Llwytho...

DDB2, an Essential Mediator of Premature Senescence

Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and cancer therapy. Here, we reveal a novel function of the nucleotide excision repair protein DDB2 in the accumulation of ROS in a manner that is essential for premature senescence. DDB2-d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roy, Nilotpal, Stoyanova, Tanya, Dominguez-Brauer, Carmen, Park, Hyun Jung, Bagchi, Srilata, Raychaudhuri, Pradip
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876515/
https://ncbi.nlm.nih.gov/pubmed/20351176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01480-09
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