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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

Activated AMPK protects the heart from cardiac ischemia-reperfusion (IR) injury and is associated with inhibition of mitochondrial permeability transition pore (PTP) opening. On the other hand, pharmacological inhibition of the PTP reduces infarct size and improves cardiac function. However, it is u...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Barreto-Torres, Giselle, Javadov, Sabzali
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802016/
https://ncbi.nlm.nih.gov/pubmed/27051413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9282087
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