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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

Activated AMPK protects the heart from cardiac ischemia-reperfusion (IR) injury and is associated with inhibition of mitochondrial permeability transition pore (PTP) opening. On the other hand, pharmacological inhibition of the PTP reduces infarct size and improves cardiac function. However, it is u...

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Detalles Bibliográficos
Publicado en:PPAR Res
Main Authors: Barreto-Torres, Giselle, Javadov, Sabzali
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802016/
https://ncbi.nlm.nih.gov/pubmed/27051413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9282087
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