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Thermodynamics of Rev–RNA Interactions in HIV-1 Rev–RRE Assembly

The HIV-1 protein Rev facilitates the nuclear export of intron-containing viral mRNAs by recognizing a structured RNA site, the Rev-response-element (RRE), contained in an intron. Rev assembles as a homo-oligomer on the RRE using its α-helical arginine-rich-motif (ARM) for RNA recognition. One uniqu...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Jayaraman, Bhargavi, Mavor, David, Gross, John D., Frankel, Alan D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801481/
https://ncbi.nlm.nih.gov/pubmed/26422686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00876
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