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An α-Helical Peptidomimetic Inhibitor of the HIV-1 Rev-RRE Interaction
The interaction between the HIV-1 Rev protein and the Rev-Responsive Element (RRE) RNA is an attractive target for anti-viral therapy. We have designed α-helical peptidomimetics of Rev-like peptides using sidechain-sidechain macrolactam formation between positions i and i+4. One peptidomimetic havin...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566309/ https://ncbi.nlm.nih.gov/pubmed/16536504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0582051 |
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