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Interferon gamma/NADPH oxidase defense system in immunity and cancer
As a part of cellular pathogen defense, IFNγ triggers induction of NADPH oxidase NOX2, which produces superoxide into phagosomes of immune cells. Recent data show that a similar mechanism can also operate in IFNγ-mediated anticancer control. IFNγ is capable of inducing expression of constitutively a...
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| Udgivet i: | Oncoimmunology |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801460/ https://ncbi.nlm.nih.gov/pubmed/27057461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1080416 |
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