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Interferon gamma/NADPH oxidase defense system in immunity and cancer

As a part of cellular pathogen defense, IFNγ triggers induction of NADPH oxidase NOX2, which produces superoxide into phagosomes of immune cells. Recent data show that a similar mechanism can also operate in IFNγ-mediated anticancer control. IFNγ is capable of inducing expression of constitutively a...

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Publicat a:Oncoimmunology
Autors principals: Hodny, Zdenek, Reinis, Milan, Hubackova, Sona, Vasicova, Pavla, Bartek, Jiri
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801460/
https://ncbi.nlm.nih.gov/pubmed/27057461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1080416
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