Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification

Detecting point mutation of human cancer cells quickly and accurately is gaining in importance for pathological diagnosis and choice of therapeutic approach. In the present study, we present novel methodology, peptide nucleic acid—locked nucleic acid mediated loop-mediated isothermal amplification (...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Itonaga, Masahiro, Matsuzaki, Ibu, Warigaya, Kenji, Tamura, Takaaki, Shimizu, Yuki, Fujimoto, Masakazu, Kojima, Fumiyoshi, Ichinose, Masao, Murata, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801409/
https://ncbi.nlm.nih.gov/pubmed/26999437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151654
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