Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification

Detecting point mutation of human cancer cells quickly and accurately is gaining in importance for pathological diagnosis and choice of therapeutic approach. In the present study, we present novel methodology, peptide nucleic acid—locked nucleic acid mediated loop-mediated isothermal amplification (...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Itonaga, Masahiro, Matsuzaki, Ibu, Warigaya, Kenji, Tamura, Takaaki, Shimizu, Yuki, Fujimoto, Masakazu, Kojima, Fumiyoshi, Ichinose, Masao, Murata, Shin-ichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801409/
https://ncbi.nlm.nih.gov/pubmed/26999437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151654
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