Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification

Detecting point mutation of human cancer cells quickly and accurately is gaining in importance for pathological diagnosis and choice of therapeutic approach. In the present study, we present novel methodology, peptide nucleic acid—locked nucleic acid mediated loop-mediated isothermal amplification (...

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Veröffentlicht in:PLoS One
Hauptverfasser: Itonaga, Masahiro, Matsuzaki, Ibu, Warigaya, Kenji, Tamura, Takaaki, Shimizu, Yuki, Fujimoto, Masakazu, Kojima, Fumiyoshi, Ichinose, Masao, Murata, Shin-ichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801409/
https://ncbi.nlm.nih.gov/pubmed/26999437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151654
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