Computational and nonglycosylated systems: a simpler approach for development of nanosized PEGylated proteins

Cysteine PEGylation includes several steps, and is difficult to manage in practice. In the current investigation, the cysteine PEGylation of erythropoietin analogs was examined using computational and nonglycosylated systems to define a simpler approach for specific PEGylation. Two model analogs (E3...

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Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Mirzaei, Hadi, Kazemi, Bahram, Bandehpour, Mojgan, Shoari, Alireza, Asgary, Vahid, Ardestani, Mehdi Shafiee, Madadkar-Sobhani, Armin, Cohan, Reza Ahangari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801162/
https://ncbi.nlm.nih.gov/pubmed/27042012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S98323
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