Computational and nonglycosylated systems: a simpler approach for development of nanosized PEGylated proteins

Cysteine PEGylation includes several steps, and is difficult to manage in practice. In the current investigation, the cysteine PEGylation of erythropoietin analogs was examined using computational and nonglycosylated systems to define a simpler approach for specific PEGylation. Two model analogs (E3...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Mirzaei, Hadi, Kazemi, Bahram, Bandehpour, Mojgan, Shoari, Alireza, Asgary, Vahid, Ardestani, Mehdi Shafiee, Madadkar-Sobhani, Armin, Cohan, Reza Ahangari
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801162/
https://ncbi.nlm.nih.gov/pubmed/27042012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S98323
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