Design, modeling, expression, and chemoselective PEGylation of a new nanosize cysteine analog of erythropoietin

BACKGROUND: Recombinant human erythropoietin (rhEPO) is considered to be one of the most pivotal pharmaceutical drugs in the market because of its clinical application in the treatment of anemia-associated disorders worldwide. However, like other therapeutic proteins, it does not have suitable pharm...

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Detalhes bibliográficos
Main Authors: Cohan, Reza Ahangari, Madadkar-Sobhani, Armin, Khanahmad, Hossein, Roohvand, Farzin, Aghasadeghi, Mohammad Reza, Hedayati, Mohammad Hossein, Barghi, Zahra, Ardestani, Mehdi Shafiee, Inanlou, Davoud Nouri, Norouzian, Dariush
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131188/
https://ncbi.nlm.nih.gov/pubmed/21753873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S19081
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