Cargando...

A new view of transcriptome complexity and regulation through the lens of local splicing variations

Alternative splicing (AS) can critically affect gene function and disease, yet mapping splicing variations remains a challenge. Here, we propose a new approach to define and quantify mRNA splicing in units of local splicing variations (LSVs). LSVs capture previously defined types of alternative spli...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:eLife
Main Authors: Vaquero-Garcia, Jorge, Barrera, Alejandro, Gazzara, Matthew R, González-Vallinas, Juan, Lahens, Nicholas F, Hogenesch, John B, Lynch, Kristen W, Barash, Yoseph
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801060/
https://ncbi.nlm.nih.gov/pubmed/26829591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11752
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!