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A new view of transcriptome complexity and regulation through the lens of local splicing variations
Alternative splicing (AS) can critically affect gene function and disease, yet mapping splicing variations remains a challenge. Here, we propose a new approach to define and quantify mRNA splicing in units of local splicing variations (LSVs). LSVs capture previously defined types of alternative spli...
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| Опубликовано в: : | eLife |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801060/ https://ncbi.nlm.nih.gov/pubmed/26829591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11752 |
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