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Two New Isotype-Specific Switching Activities Detected for Ig Class Switching()
Ig class switch recombination (CSR) occurs by an intrachromosomal deletional process between switch (S) regions in B cells. To facilitate the study of CSR, we derived a new B cell line, 1.B4.B6, which is uniquely capable of μ→γ3, μ→ε, and μ→α, but not μ→γ1 CSR at its endogenous loci. The 1.B4.B6 cel...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801030/ https://ncbi.nlm.nih.gov/pubmed/11884453 |
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