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Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

Ovarian cancer is associated with a leukocyte infiltrate and high levels of chemokines such as CCL2. We tested the hypothesis that CCL2 inhibition can enhance chemotherapy with carboplatin and paclitaxel. Elevated CCL2 expression was found in three non‐MDR paclitaxel resistant ovarian cancer lines E...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Moisan, Francois, Francisco, Edgar B., Brozovic, Anamaria, Duran, George E., Wang, Yan C., Chaturvedi, Shalini, Seetharam, Shobha, Snyder, Linda A., Doshi, Parul, Sikic, Branimir I.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801026/
https://ncbi.nlm.nih.gov/pubmed/24816187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.016
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