The miR‐200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR‐3 and MES‐OV cells

We studied the role of miRNA‐200 family members in cellular sensitivity to paclitaxel and carboplatin, using two ovarian cancer cell lines, OVCAR‐3 and MES‐OV, and their paclitaxel resistant variants OVCAR‐3/TP and MES‐OV/TP. Both resistant variants display a strong epithelial‐mesenchymal transition...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Brozovic, Anamaria, Duran, George E., Wang, Yan C., Francisco, E. Brian, Sikic, Branimir I.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788969/
https://ncbi.nlm.nih.gov/pubmed/26025631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.04.015
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