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Dynamic Monitoring of Oxidative DNA Double Strand Break and Repair in Cardiomyocytes

DNA double strand breaks (DSBs) are most dangerous lesions. To determine whether oxidative stress can induce DSBs and how they are repaired in cardiomyocytes (CMs), cultured neonatal rat CMs were treated with different doses of H(2)O(2) and followed for up to 72 hours for monitoring the spatiotempor...

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Détails bibliographiques
Publié dans:Cardiovasc Pathol
Auteurs principaux: Ye, Bo, Hou, Ning, Xiao, Lu, Xu, Yifan, Xu, Haodong, Li, Faqian
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801000/
https://ncbi.nlm.nih.gov/pubmed/26764141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2015.10.010
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