DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

Plasmid DNAs expressing influenza virus hemagglutinin glycoproteins have been tested for their ability to raise protective immunity against lethal influenza challenges of the same subtype. In trials using two inoculations of from 50 to 300 micrograms of purified DNA in saline, 67-95% of test mice an...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fynan, E F, Webster, R G, Fuller, D H, Haynes, J R, Santoro, J C, Robinson, H L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11478
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