DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

Plasmid DNAs expressing influenza virus hemagglutinin glycoproteins have been tested for their ability to raise protective immunity against lethal influenza challenges of the same subtype. In trials using two inoculations of from 50 to 300 micrograms of purified DNA in saline, 67-95% of test mice an...

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Autori principali: Fynan, E F, Webster, R G, Fuller, D H, Haynes, J R, Santoro, J C, Robinson, H L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC48007/
https://ncbi.nlm.nih.gov/pubmed/8265577
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