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Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment

Breast cancer is a heterogeneous disease, at both an inter- and intra-tumoural level. Appreciating heterogeneity through the application of biomarkers and molecular signatures adds complexity to tumour taxonomy but is key to personalising diagnosis, treatment and prognosis. The extent to which heter...

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Vydáno v:Sci Rep
Hlavní autoři: Buckley, Niamh E., Forde, Claire, McArt, Darragh G., Boyle, David P., Mullan, Paul B., James, Jacqueline A., Maxwell, Perry, McQuaid, Stephen, Salto-Tellez, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800308/
https://ncbi.nlm.nih.gov/pubmed/26996207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23383
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