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Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment

Breast cancer is a heterogeneous disease, at both an inter- and intra-tumoural level. Appreciating heterogeneity through the application of biomarkers and molecular signatures adds complexity to tumour taxonomy but is key to personalising diagnosis, treatment and prognosis. The extent to which heter...

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Publicat a:Sci Rep
Autors principals: Buckley, Niamh E., Forde, Claire, McArt, Darragh G., Boyle, David P., Mullan, Paul B., James, Jacqueline A., Maxwell, Perry, McQuaid, Stephen, Salto-Tellez, Manuel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800308/
https://ncbi.nlm.nih.gov/pubmed/26996207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23383
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