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Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia

Histone deacetylases (HDACs) are a key component of the epigenetic machinery regulating gene expression, and behave as oncogenes in several cancer types, spurring the development of HDAC inhibitors (HDACi) as anticancer drugs. This review discusses new results regarding the role of HDACs in cancer a...

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Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Ceccacci, Elena, Minucci, Saverio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800301/
https://ncbi.nlm.nih.gov/pubmed/26908329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.36
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